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Ching-Shih Chen Selected Research

2,4-thiazolidinedione (thiazolidinedione)

11/2015Development of Potent Adenosine Monophosphate Activated Protein Kinase (AMPK) Activators.
12/2012Activation of silenced tumor suppressor genes in prostate cancer cells by a novel energy restriction-mimetic agent.
7/2009Thiazolidinediones mimic glucose starvation in facilitating Sp1 degradation through the up-regulation of beta-transducin repeat-containing protein.
4/2009PPARgamma-independent antitumor effects of thiazolidinediones.
5/2006Peroxisome proliferator-activated receptor gamma-independent repression of prostate-specific antigen expression by thiazolidinediones in prostate cancer cells.

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Ching-Shih Chen Research Topics

Disease

105Neoplasms (Cancer)
01/2020 - 09/2002
39Prostatic Neoplasms (Prostate Cancer)
05/2019 - 04/2002
20Breast Neoplasms (Breast Cancer)
01/2020 - 01/2005
16Carcinogenesis
12/2015 - 06/2004
7Neoplasm Metastasis (Metastasis)
01/2018 - 11/2009
7Hepatocellular Carcinoma (Hepatoma)
03/2014 - 10/2007
6Pancreatic Neoplasms (Pancreatic Cancer)
04/2019 - 02/2006
6Triple Negative Breast Neoplasms
11/2017 - 11/2011
6Multiple Myeloma
01/2014 - 08/2007
5Adenocarcinoma
03/2013 - 10/2005
4Body Weight (Weight, Body)
01/2020 - 05/2008
4Inflammation (Inflammations)
07/2018 - 06/2011
4Lymphoma (Lymphomas)
04/2016 - 01/2008
4Thyroid Neoplasms (Thyroid Cancer)
01/2016 - 11/2007
4B-Cell Chronic Lymphocytic Leukemia (Chronic Lymphocytic Leukemia)
08/2014 - 01/2008
4Starvation
03/2013 - 09/2008
4B-Cell Lymphoma (Lymphoma, B Cell)
03/2009 - 03/2005
3Mantle-Cell Lymphoma (Lymphoma, Mantle Cell)
09/2015 - 06/2010
3Hypoxia (Hypoxemia)
04/2015 - 11/2011
3Glioblastoma (Glioblastoma Multiforme)
05/2014 - 11/2005
3Glioma (Gliomas)
05/2014 - 08/2006
3Leukemia
12/2013 - 09/2007
3BCR-ABL Positive Chronic Myelogenous Leukemia (Chronic Myelogenous Leukemia)
10/2013 - 05/2005
3Acoustic Neuroma (Acoustic Neurinoma)
01/2012 - 06/2009
3Lung Neoplasms (Lung Cancer)
01/2012 - 04/2006
2Cachexia
01/2020 - 12/2015
2Squamous Cell Carcinoma of Head and Neck
07/2018 - 06/2012
2Melanoma (Melanoma, Malignant)
01/2016 - 04/2010
2Liver Neoplasms (Liver Cancer)
12/2015 - 03/2014

Drug/Important Bio-Agent (IBA)

31Histone Deacetylase InhibitorsIBA
01/2020 - 10/2004
23Celecoxib (Celebrex)FDA Link
04/2019 - 04/2002
20Pharmaceutical PreparationsIBA
04/2016 - 02/2005
18Histone Deacetylases (Histone Deacetylase)IBA
11/2017 - 08/2005
18Proteins (Proteins, Gene)FDA Link
03/2016 - 05/2005
15Phosphotransferases (Kinase)IBA
03/2016 - 06/2004
13OSU 03012IBA
04/2019 - 02/2006
11Histones (Histone)IBA
12/2016 - 01/2004
11PPAR gammaIBA
03/2010 - 02/2005
9Phosphatidylinositols (Phosphatidylinositol)IBA
04/2019 - 07/2003
9Biomarkers (Surrogate Marker)IBA
11/2017 - 08/2007
9Fingolimod Hydrochloride (FTY720)FDA Link
09/2015 - 09/2007
8integrin-linked kinaseIBA
11/2018 - 09/2011
6Protein Kinases (Protein Kinase)IBA
04/2019 - 04/2008
6Antineoplastic Agents (Antineoplastics)IBA
11/2015 - 11/2005
6Biological ProductsIBA
09/2015 - 03/2010
6Glucose (Dextrose)FDA LinkGeneric
10/2014 - 09/2008
6Cyclin D1IBA
12/2011 - 04/2005
6Troglitazone (Rezulin)FDA Link
04/2009 - 04/2005
6Cyclooxygenase 2 (Cyclooxygenase-2)IBA
08/2007 - 04/2002
5Androgen Receptors (Androgen Receptor)IBA
01/2020 - 04/2007
5AndrogensIBA
01/2020 - 04/2002
5ErbB Receptors (EGF Receptor)IBA
04/2016 - 01/2005
5Messenger RNA (mRNA)IBA
12/2015 - 10/2005
52,4-thiazolidinedione (thiazolidinedione)IBA
11/2015 - 05/2006
5indole-3-carbinolIBA
05/2010 - 08/2007
5ThiazolidinedionesIBA
07/2009 - 03/2005
4Protein Isoforms (Isoforms)IBA
11/2017 - 12/2012
4Small Interfering RNA (siRNA)IBA
04/2016 - 01/2014
4DNA (Deoxyribonucleic Acid)IBA
04/2014 - 06/2007
4Deoxyglucose (2 Deoxy D glucose)IBA
12/2012 - 03/2010
4Phosphatidylinositol 3-Kinase (1 Phosphatidylinositol 3 Kinase)IBA
01/2012 - 07/2003
4Lenalidomide (CC 5013)FDA Link
09/2011 - 05/2008
4VorinostatFDA Link
01/2011 - 09/2006
4NF-kappa B (NF-kB)IBA
05/2010 - 04/2008
4ciglitazoneIBA
03/2010 - 04/2005
3GemcitabineFDA Link
04/2019 - 02/2006
3Estrogen ReceptorsIBA
04/2019 - 04/2008
3Oxygen (Dioxygen)IBA
10/2018 - 01/2014
3IGF Type 1 Receptor (IGF 1 Receptor)IBA
01/2018 - 11/2006
3OSU-53IBA
01/2016 - 11/2011
3IntegrinsIBA
12/2015 - 01/2012
3TensinsIBA
11/2015 - 05/2006
3Adenosine Monophosphate (AMP)IBA
11/2015 - 11/2011
3Phosphoric Monoester Hydrolases (Phosphatases)IBA
11/2015 - 03/2015
3OSU-2SIBA
09/2015 - 06/2011
3LuciferasesIBA
06/2015 - 11/2009
3Hormones (Hormone)IBA
03/2015 - 06/2012
3Ubiquitin-Protein Ligases (Ubiquitin-Protein Ligase)IBA
01/2012 - 09/2007
3benzamideIBA
01/2012 - 07/2008
3beta CateninIBA
01/2010 - 09/2007
3(1- (4- chloro- 3- nitrobenzenesulfonyl)- 1H- indol- 3- yl)- methanolIBA
11/2009 - 08/2007
3Succinic Acid (Succinate)IBA
09/2009 - 04/2006
3beta-Transducin Repeat-Containing ProteinsIBA
07/2009 - 09/2007
3SurvivinIBA
10/2007 - 05/2006
3Cyclooxygenase 2 Inhibitors (COX-2 Inhibitors)IBA
05/2006 - 04/2002
2Notch1 ReceptorIBA
01/2020 - 01/2016
2Facilitative Glucose Transport Proteins (Glucose Transporter)IBA
04/2019 - 10/2014
2TamoxifenFDA LinkGeneric
04/2019 - 04/2008
2EnzymesIBA
07/2018 - 10/2009
2Mitogen-Activated Protein Kinase Kinases (MEKs)IBA
01/2018 - 09/2015
2Estrogens (Estrogen)FDA Link
04/2016 - 04/2008
2Endoplasmic Reticulum Chaperone BiPIBA
03/2016 - 02/2012
2CytokinesIBA
01/2016 - 12/2015
2OSU-CG5IBA
12/2015 - 03/2013
2Ligases (Synthetase)IBA
12/2015 - 04/2014
2Trastuzumab (Herceptin)FDA Link
11/2015 - 11/2006

Therapy/Procedure

36Therapeutics
01/2020 - 06/2004
7Drug Therapy (Chemotherapy)
10/2016 - 05/2006
6Oral Administration
12/2016 - 10/2007
2Radiotherapy
10/2018 - 02/2012